Supervisors: Pr. Thierry VANDAMME, Dr. Nicolas ANTON & Dr. Guillaume CONZATTI
Overview
The principal goal of the topic “Biogalenic and therapeutic innovations” is to develop novel systems for both therapy, or tissue engineering, and diagnostics. These systems are created using various technical approaches and innovative formulations containing molecules of interest, as well as the development of functional systems.
Multidisciplinary, the topic "Biogalenic and therapeutic innovations" spans a wide range of scientific fields, including formulation, chemical modification, processes, nanoscience and the sciences of semi-solid and solid materials. It also leverages the expertise of other topics within the UMR 1260 Regenerative Nanomedicine and the technological platforms of the CRBS.
Scientific expertise
Design and development of formulations
- Emulsions
- Dry dosage forms
- Innovative drug delivery systems
Smart nanotechnologies
- Biopharmaceutics
- Drug screening
- Medical imaging and theranostics
Stimuli-responsive biomaterials
- Natural and synthetic polymers
- Synthesis, formulation and evaluation
Technical expertise
Drug dissolution and release profiles
- Continuous flow processes
- UV-Vis and fluorescence spectrometry
Physicochemistry of particles, nanoparticles and interfaces
- Particle size analysis (granulometry)
- Drop tensiometry and interfacial rheology
- Surface property characterization of nanoparticles
Chemistry and formulation
- Polymer synthesis
- Chemical functionalization
- Nano-emulsification via spontaneous and high-energy methods
- Multiple emulsions
- Optical microscopy
- Lyophilization
Formulation and material characterization
- Oscillatory rheology
- Stability studies
Grants
- 2026 ANR Rigel - Ring-shaped gastoretentive system for controlled drug release (PI Thierry VANDAMME)
- 2024 ANR FluoLLPS - Fluorescence tools to characterize Liquid-Liquid Phase Separation (PI Nicolas ANTON)
- 2023 IDEX “recherche exploratoire” - Innovative physicochemical and fluorescent tools to characterize liquid-liquid phase separation (PI Nicolas ANTON)
- 2023 PHC Utique 2023 - Development of innovative pH-sensitive liposomes and nano-emulsions for organ preservation solutions (PI Nicolas ANTON)
- 2022 ANR SenEmul - “Green” bio-mimetic platform based on lipid nanoemulsions for detection of endothelial senescence (PI Nicolas ANTON / Thierry VANDAMME)
- 2021 ANR PAANIC - Pulmonary Administration of Antibiotic Nano-emulsion to treat gram-negative bacteria InfeCtions (Consortium coordinator Nicolas ANTON)
- 2020 IDEX “attractivité” (PI Guillaume CONZATTI)
- 2020 ANR LABRICON - Laser-assisted fabrication of silicone-based patches for transdermal drug release (PI Thierry VANDAMME)
- 2017 ANR BioCaps - Programmable release of drugs by rolled up biocapsules (PI Thierry VANDAMME)